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Details of the genetic analyses are available in the Supplementary Information

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FOXO4-DRI counteracts frailty and loss of renal function in naturally aged mice Encouraged by these results, we decided to challenge whether FOXO4-DRI could also target senescence and tissue homeostasis in normal mice that were allowed to age naturally

77 Administration of oral L-Cysteine to patients with cirrhosis has been noted to cause a twofold greater maximal plasma cysteine concentration and plasma elimination half-life, and a delayed excretion of metabolic end products when compared with those of controls